A bottle of Shaker Anodyne from Enfield Shaker Village in New Hampshire

A Trusted Name in a Dubious Drug Market

Amid the fraud and flimflam of early drug markets, Shakers stood for purity, creating a brand others were eager to exploit.
Vibrant sassafras leaves create a colorful understory in the woods near the Great Marsh Area of the Massachusetts North Shore. Sassafras leaves are unique for their three distinct shapes: a simple oval, a two-lobed "mitten" shape, and a three-lobed shape.

Sassafras: From Scent to Science in American Medicine

How did sassafras go from cure-all to carcinogen? Its history links Indigenous knowledge, colonial trade, and modern scientific debate.
The golden death mask of Egyptian pharaoh Tutankhamen, 1950

The Pharaoh’s Curse or the Pharaoh’s Cure?

A toxic fungus from King Tutankhamun’s tomb yields cancer-fighting compounds.
Wilhelm Reich portrait

Wilhelm Reich: Twice Burned

A psychoanalyst and physician, Reich fled the Nazis only to be detained by the US as an “enemy alien” during World War II. And then came the sexual revolution.
A 19th century madstone

Dubious Medicine on the Texas Frontier

If you got sick in the Texas frontier area in the decades before the Civil War, your options were all pretty bad.
A stethoscope

Second Opinions: On Intellectual Humility and Medicine

What happens when doctors admit they don't know everything?
An illustration of a woman distilling, 1691

The Home Science Labs of English Noblewomen

In the eighteenth century, elite women with a scientific bent often turned to distilling medicines, a craft that helped them participate in experimentation.
Stevia rebaudiana

Stevia’s Global Story

Native to Paraguay, Ka’a he’e followed a circuitous path through Indigenous medicine, Japanese food science, and American marketing to reach the US sweeteners market.
Hospital emergency room entrance sign

Medicalizing Domestic Violence

What happens when experts position domestic violence inside a biomedical model of care?
Cordyceps militaris

“There’s Gold in Them Thar Fungi”: Cordyceps as Cash Crop

A fungus in the genus Cordyceps has us running scared. But some of its species are worth more than their weight in gold.