“If someone is from the Amazon,” says Evgenia Fotiou, an anthropologist who studies Western ayahuasca usage, “they bring some legitimacy” to an ayahuasca ritual.

This plant’s animal-like behavior and alleged love-provoking abilities have sparked the imagination of everyone from early modern yogis to today’s scientists.

There’s always been some fuzziness in our distinctions between medicine and recreational drugs. Just look at nitrous oxide.

One bioethics scholar wonders if modern medicine is in danger of pathologizing what are painful, but normal, human experiences.

In a perplexing recent study, researchers dosed octopuses. Turns out, scientists have long studied the similarities between cephalopod and human brains.

Treating addiction can have a toll on doctors, who may find themselves confused and challenged by the addicts' behavior.

Researchers found that Psilocybin and other hallucinogens may prove helpful in their ability to quiet a portion of the brain connected to depression.

Drug advertising is a longstanding issue in the U.S, tangled with patients’ rights to make their own decisions, doctors’ professional status, and the ethics of profiting from powerful drugs.

As policymakers seek solutions for the ongoing opioid epidemic, it's worth remembering how sensationalist reporting can lead to troubling responses.

Regulations banning performance-enhancing drugs raise as many questions as they answer.